Incidence of constitutive and inducible clindamycin resistance among hospital-associated Staphylococcus aureus
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چکیده
منابع مشابه
Incidence of constitutive and inducible clindamycin resistance among hospital-associated Staphylococcus aureus
Clindamycin is one of the important alternative antibiotics in the therapy of Staphylococcus aureus infections. Clinical failure of clindamycin therapy has been reported due to multiple mechanisms that confer resistance to macrolides, lincosamides and Streptogramin B (MLSB) antibiotics. In vitro routine tests for clindamycin susceptibility may fail to detect inducible clindamycin resistance due...
متن کاملInducible clindamycin resistance among Staphylococcus aureus isolates
Introduction: Clindamycin is considered an useful alternate drug in penicillin-allergic patients in the treatment of skin & soft tissue infections caused by Staphylococcus aureus. Staphylococcus spp. can be resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but may appear susceptible to clin...
متن کاملPrevalence of inducible clindamycin resistance among community- and hospital-associated Staphylococcus aureus isolates.
Methicillin-resistant Staphylococcus aureus (MRSA) infections have become common among both hospitalized and nonhospitalized patients. Optimal outpatient therapy for MRSA infections has yet to be determined, but this matter is complicated by the possibility of inducible macrolide-lincosamide-streptogramin B resistance (MLSBi). We studied the prevalence of MLSBi in community- and hospital-associ...
متن کاملInducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital.
INTRODUCTION Staphylococcus aureus is one of the most common pyogenic bacteria. They are notorious for developing prompt resistance to newer antimicrobials. With increasing incidence of methicillin-resistant S. aureus (MRSA) isolates, the treatment options are also becoming limited. Clindamycin is an excellent drug for skin and soft tissue infections, but resistance mediated by the inducible ph...
متن کاملConstitutive and Inducible Clindamycin Resistance Frequencies among Staphylococcus sp. Coagulase Negative Isolates in Al-Basrah Governorate, Iraq
Background: Antibiotics called macrolide, lincosamide and streptogramin B (MLSB) are being used to treat staphylococci infections. Multiple pathways that impart resistance to MLSB antibiotics have been confirmed to cause clinical failure. The present work aimed to determine the frequency of constitutive and inducible clindamycin resistant among coagulase-negative staphylococci (CoNS) isolates o...
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ژورنال
عنوان ژورنال: 3 Biotech
سال: 2013
ISSN: 2190-572X,2190-5738
DOI: 10.1007/s13205-013-0133-5